Monthly Archives: November 2025

I’m Not a Doomer. I’m the Engineer Who’s Spent Three Decades in the Trenches.

And I’m done watching the same suppression playbook run for the fourth decade in a row. November 22, 2025 John Coates (@rfsafe) Founder, RF SAFE (est. 1998) Inventor on multiple Li-Fi / photonics patents Former believer that “we can engineer our way out of this” I’m not here to scream “turn it all off.” I’m […]

The S4–Mitochondria Rosetta Stone

A Comprehensive Mechanistic Synthesis of Non-Thermal Radiofrequency Biological Effects in 2025 Why the Same First Domino Explains Cancer, Male Infertility, Autoimmune Dysregulation, Metabolic Collapse, and Rising Childhood Leukemias, and the Global Explosion of Chronic Disease John R. Coates Founder, RF SAFE (est. 1998) @rfsafe 22 November 2025 Executive Summary After 30 years and >30,000 peer-reviewed […]

S4 Timing Fidelity — A Mechanistic Synthesis for Pulsed RF‑EMF Effects and “EHS”

The working hypothesis is that many non‑thermal biological effects from wireless systems originate in timing errors at voltage‑gated ion channels (VGICs). The S4 helix—the positively charged voltage sensor in VGICs—opens and closes channels in response to millivolt‑scale changes in local transmembrane potential. Pulsed and modulated RF fields contain low‑frequency envelopes that drive forced oscillations of […]

What non‑native EMFs really do — Ion Timing Fidelity under RF exposure, from S4 voltage sensing to mitochondrial ROS and immune dysregulation

PURPOSEThis one‑page brief explains, in plain scientific language, a single causal chain that links common indoor radiofrequency exposure to immune dysregulation and oxidative stress. It is written so policymakers, engineers, and scientists can align on both mechanism and action. THE MECHANISM IN ONE PARAGRAPHVoltage‑gated ion channels open and close when a short, positively charged protein […]

Restoring Bioelectric Timing Fidelity to Prevent Immune Dysregulation

Non‑thermal biological effects of low‑frequency/pulsed RF exposures arise from a timing‑fidelity mechanism in which external fields shift the voltage‑dependent activation energy of ion channels. Voltage‑gated channels sense transmembrane potential with the S4 helix; a local potential change ΔV\Delta VΔV across the ~1 nm sensing region shifts the barrier by ΔG=zeffe ΔV\Delta G = z_{\mathrm{eff}} e\,\Delta VΔG=zeff​eΔV. With […]