1. Multiple ROS “engines”, not just mitochondria Right now you treat mitochondria as the main ROS amplifier. The broader literature says that’s only half the story. There are at least three major ROS engines that EMFs can plausibly drive once ionic balance is disturbed: Mitochondrial ETC – what you already emphasize. NADPH oxidases (NOX/DUOX family) […]
Category Archives: QuantaDose Press Releases
1. Epigenetic Programming and Memory of EMF-Induced Perturbations 1.1 Conceptual Overview The original S4/IFO–mitochondria model explains how non‑thermal EMFs generate ROS and ion‑signalling noise on fast (ms–h) timescales. To explain why brief exposures can leave long‑lived or transgenerational marks, a formal epigenetic layer is needed. Epigenetic programming provides exactly this: a set of biochemical mechanisms […]
Circadian biology typically treats light—in the optical range—as the dominant time cue for the brain’s master clock in the suprachiasmatic nucleus (SCN). Blue light enters the eye, specialized cells signal to the SCN, and the core clock machinery adjusts its timing. A growing body of work suggests that this may not be the whole story. […]
The Herzification Hypothesis: How RF Is Rewriting Human Traits Across Generations The Herzification / Bioelectric Fidelity Hypothesis Why One Mechanism Explains Cancer, Infertility, Autism, ADHD, Collapsing Empathy, and the Transgenerational Erosion of Who We Are John Coates (@rfsafe) 22 November 2025 For 99.999 % of human evolution, the electromagnetic background was essentially zero. Then, in […]
A Root‑Cause Hypothesis for Non‑Native EMFs as Entropic Waste I didn’t start RF Safe as a business plan. I started it as a promise. In 1995, my firstborn daughter, Angel Leigh Coates, died from a catastrophic neural‑tube defect. At the time, the only actionable message I could find was folate, so I did what any […]
For roughly 99.999% of our evolutionary history, brains and bodies ran on a very quiet electromagnetic background. Cells talked to themselves with: Membrane voltages Voltage‑gated ion channels Calcium spikes Mitochondrial redox states Then, in about 150 years, we changed the electrical environment more than nature did in millions. 1880s: Heinrich Hertz’s spark‑gap experiments turn Maxwell’s equations […]
And I’m done watching the same suppression playbook run for the fourth decade in a row. November 22, 2025 John Coates (@rfsafe) Founder, RF SAFE (est. 1998) Inventor on multiple Li-Fi / photonics patents Former believer that “we can engineer our way out of this” I’m not here to scream “turn it all off.” I’m […]
A Comprehensive Mechanistic Synthesis of Non-Thermal Radiofrequency Biological Effects in 2025 Why the Same First Domino Explains Cancer, Male Infertility, Autoimmune Dysregulation, Metabolic Collapse, and Rising Childhood Leukemias, and the Global Explosion of Chronic Disease John R. Coates Founder, RF SAFE (est. 1998) @rfsafe 22 November 2025 Executive Summary After 30 years and >30,000 peer-reviewed […]
The working hypothesis is that many non‑thermal biological effects from wireless systems originate in timing errors at voltage‑gated ion channels (VGICs). The S4 helix—the positively charged voltage sensor in VGICs—opens and closes channels in response to millivolt‑scale changes in local transmembrane potential. Pulsed and modulated RF fields contain low‑frequency envelopes that drive forced oscillations of […]
PURPOSEThis one‑page brief explains, in plain scientific language, a single causal chain that links common indoor radiofrequency exposure to immune dysregulation and oxidative stress. It is written so policymakers, engineers, and scientists can align on both mechanism and action. THE MECHANISM IN ONE PARAGRAPHVoltage‑gated ion channels open and close when a short, positively charged protein […]